After surgeon scientist Curtis Connors lost his arm–and his mind–he created a serum that used reptilian DNA to regrow his missing limb. Indeed, it did successfully grow back, however it also transformed him into the Super-Villain we all fear, the Lizard. Now, only one man alive can stop this raging reptile. The Spectacular Spider-Man! Will the web-slinger be able to tame this cold blooded villain? Or will the Lizard and his scaly armor be too much for our favorite neighborhood Super Hero? Find out who wins this battle of insect vs. reptile.